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題目：Super Dots for Super Resolution Imaging and Single Molecule Digital Assays

報告人：金大勇，悉尼科技大學(xué)杰出教授和南方科技大學(xué)講席教授

時間：2021年1月4日（星期一）上午10：00-11：30

地點：上海交通大學(xué)閔行校區(qū) 轉(zhuǎn)化醫(yī)學(xué)中心C5

邀請人：樊春海 院士

My labs have developed a new family of nanophotonic “Super Dots” that can up-convert infrared photons into intense visible light at the nanoscale. A single Dot can be highly doped with more than 104 ions for high brightness.

Several fascinating properties have been discovered since to allow high-throughput bio-discoveries, data storage, single nanoparticle lasing and high-security-level anti-counterfeiting applications, setting records for the tracking of single-molecule transport, super-resolution microscopy, nanoscale thermometry, and recently super-capacity single molecule digital assays and optical tweezers.

In my talk, I will present the recent new developments of super-resolution microscopy imaging and single molecule tracking techniques, including direct microscopic inspection and tracking of single upconversion nanoparticles in living cells, multi-photon near-infrared emission saturation nanoscopy using single beam scanning, Bessel beam scanning to map single nanoparticles inside tumor spheroids, nonlinear structured illumination microscopy, Fourier domain heterochromatic fusion for single beam scanning super-resolution microscopy, and axial localization and tracking of self-interference nanoparticles by lateral point spread functions.

BIOS

Dayong Jin is a Distinguished Professor at the University of Technology Sydney since 2017 and a Chair Professor at Southern University of Science and Technology since 2019.

Prof Jin obtained his PhD from Macquarie University in 2007. At Macquarie, he was promoted to Lecturer in 2010, Senior Lecturer in 2013, and Associate Professor in 2014.

At UTS, as the director, he established the Australian Research Council Industry Transformation Research Hub for Integrated Devices for End-user Analysis at Low Levels (ARC IDEAL Research Hub), the Department of Industry, Science, Energy and Resources’ Australia-China Joint Research Centre for Point of Care Testing (DISER POCT), the UTS-SUStech Joint Research Centre for Biomedical Materials & Devices, which three major programs underpin the UTS Institute for Biomedical Materials & Devices (IBMD), to transform advances in phonics and materials into disruptive biotechnologies.

His research has been in the physical, engineering and interdisciplinary sciences, with expertise covering biomedical optics, nanotechnology, microscopy, diagnostics and microfluidics devices.

Prof Jin is the winner of the Australian Museum Eureka Prize for Interdisciplinary Scientific Research in 2015, the Australian Academy of Science John Booker Medalist in 2017, and the Prime Minister’s Malcolm McIntosh Prize for Physical Scientist of the Year 2017.

金大勇，悉尼科技大學(xué)杰出教授和南方科技大學(xué)講席教授。2007年博士畢業(yè)于麥考瑞大學(xué)，2015年任悉尼科技大學(xué)教授，2017 年任杰出教授，2019年任南方科技大學(xué)講席教授。作為所長，他五年內(nèi)先后組建了澳洲科研基金委資助的可集成生物醫(yī)學(xué)器件與技術(shù)轉(zhuǎn)化中心，中澳科學(xué)與研究基金資助的便攜式體外診斷技術(shù)聯(lián)合研究中心，悉尼科大-南科大生物醫(yī)學(xué)材料和器件聯(lián)合研究中心, 和悉尼科大生物醫(yī)學(xué)材料及儀器研究所。

金大勇教授已發(fā)表SCI高水平論文150余篇、其中包括Nature及其子刊25篇。他的專業(yè)領(lǐng)域涵蓋了生物工程光學(xué)、納米探針技術(shù)、生物醫(yī)療診斷、精密光學(xué)儀器、微流控芯片等領(lǐng)域。并于2015年榮獲澳洲科研最高獎尤里卡獎交叉學(xué)科創(chuàng)新獎，2016年當(dāng)選澳大利亞百名科技創(chuàng)新領(lǐng)軍人物，2017年榮獲澳洲科學(xué)院工程科學(xué)獎，以及2017年榮獲澳大利亞總理獎 - 年度理學(xué)家獎。

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